High Quality Raw Pramoxine Hydrochloride Powder CAS 637-58-1 Pramoxine HCl for Pain Killer
Pramoxine Hydrochloride is a topical anesthetic and used as an antipruritic too. Chemical name is p-n butoxyphenyl gammamorpholinopropyl ether hydrochloride. During research, Pramoxine Hydrochloride stood out among a series of alkoxy aryl alkamine ethers as an especially great topical local anesthetic agent. Pharmacologic study revealed Pramoxine Hydrochloride to be very potent and of low acute toxicity, well tolerated by most mucous membranes and of a low sensitizing index. Pramoxine Hydrochloride reduces the permeability of neuronal membranes to sodium ions, blocking initiation and conduction of nerve impulse. Depolarization and repolarization of excitable neural membranes is thus inhibited by Pramoxine Hydrochloride, leading to the numb sensation.
Pramoxine Hydrochloride Powder CAS 637-58-1 Basic Information:
Name |
Pramoxine hydrochloride |
CAS |
637-58-1 |
Molecular formula |
C17h28clno3 |
EINECS number |
211-293-1 |
Melting Point |
181-183 Deg C |
Boiling Point |
427 °c at 760 Mmhg |
Molecular Weight |
329.86 |
Appearance |
White Powder |
storage temp. |
2-8°C |
Purity |
>99% |
Application
Pramoxine is used to temporarily relieve itching and pain caused by minor skin irritation such as minor burns/cuts/scrapes, sunburn, eczema, insect bites, cold sores, or rashes from poison ivy, poison oak, or poison sumac. Some products containing pramoxine are also used to temporarily relieve the itching and discomfort from hemorrhoids and certain other problems of the genital/anal area (such as anal fissures, itching around the vagina/rectum).
Pramoxine belongs to a class of drugs known as local anesthetics. It works by numbing the skin to block the feelings of pain and itching.
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